Nutrition · Document 11 of 24
Lactose Tolerance
Sample Subject's predicted lactase persistence into adulthood, read from the MCM6 regulatory region upstream of LCT. All values below are synthetic and for demonstration only.
2 findings
2 Tier 3
Reviewed 2026-01-15
Provenance
Per-Gene Findings
Filter:
MCM6 — Lactase-Persistence Allele (−13910)
MCM6 regulatory region · LCT enhancer
PubMedTier 3
rs4988235
2:136,608,646
AG
The AG genotype carries one lactase-persistence allele in the MCM6 enhancer upstream of LCT. This allele supports continued lactase expression into adulthood.
Source: PubMed PMID 11788828 ↗ · dbSNP rs4988235 ↗
MCM6 — Linked Persistence Allele (−22018)
MCM6 regulatory region · haplotype support
dbSNPTier 3
rs182549
2:136,616,754
CT
The CT genotype carries a second lactase-persistence-linked allele in the same MCM6 region. This variant co-segregates with the −13910 persistence haplotype.
Source: dbSNP rs182549 ↗
Genotype Table
| rsID | chr:pos | Genotype | Gene | Significance |
|---|---|---|---|---|
rs4988235 | 2:136,608,646 | AG | MCM6 | Tier 3 |
rs182549 | 2:136,616,754 | CT | MCM6 | Tier 3 |
Consult your prescribing clinician. This HelixlyAI report is a synthetic demonstration generated from a consumer DNA export. It is not a diagnosis, prescription, or substitute for professional medical advice. Do not start, stop, or change any medication based on this document. Genotype is one of many factors influencing drug response.